DuoMAG MP

The DuoMAG MP TMS system for monophasic transcranial magnetic stimulation boasts a durable, robust, and compact design with a high-energy stimulation output for best-in-class TMS research.

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DuoMAG MP

DuoMAG MP

What is TMS and why is it used?

Transcranial Magnetic Stimulation (TMS) can be used by neuroscientists to measure the activity and function of specific brain circuits in humans. Through the placement of an electromagnetic coil on a patient's head, the TMS system can generate a very strong magnetic field that passes through the scalp and into the individual's targeted brain regions in order to induce action potentials in the subject.

The most robust and widely accepted use of TMS is in the measurement of the connections between the primary motor cortex and a muscle to evaluate damage in patients suffering from neurological diseases and conditions such as stroke, multiple sclerosis, amyotrophic lateral sclerosis, movement disorders, motor neurone disease, migraine, and other injuries and disorders that affect the facial and cranial nerves and the spinal cord.

For non-invasive brain stimulation studies concentrating on research in this area, Brainbox is proud to offer the powerful DuoMAG MP single-pulse, monophasic stimulator.

The DuoMAG MP

The DuoMAG MP is a powerful, and user-friendly TMS machine, capable of delivering high energy pulses to a subject at an unrivalled 2Hz frequency. The DuoMAG capacitor delivers pulses of up to 700J from the highly-portable stimulator module, with the compact design allowing for the device to be mounted on a desktop or on a proprietary cart device (pictured) to allow for ultimate ease of movement between laboratories.

DuoMAG MP Cart Configuration

Compatible with a comprehensive range of coils for maximum control over stimulation site, subject, and protocol, the DuoMAG MP system offers the user the option to easily configure and activate the stimulator by means of the in-built coil controls for setting intensity and triggering TMS; control via an external computer or device; or by means of the TTL port located on the rear of the stimulator module.

DuoMAG Coil Controls

For further flexibility of control, the DuoMAG MP can also be controlled by several third-party applications by means of an API, which the Brainbox team can help in setting up.

An integrated screen on the front of the stimulator module allows the user to quickly and easily view the stimulator status and output intensity at all times.

DuoMAG Intensity Screen

For studies exploring the motor cortex, the DuoMAG MP can be configured with the proprietary DuoMAG software and a four-channel electromyography (EMG) headbox, allowing researchers to record and analyse motor evoked potentials (MEPs) during their TMS experiment.

Fully Upgradeable for Expanded Research Needs

The DuoMAG MP range of monophasic TMS systems boasts a unique, modular construction that allows users to upgrade and expand their device's capabilities as research requirements change.

DuoMAG MP-Dual

Two DuoMAG MP stimulators can be combined into a single system - the DuoMAG MP-Dual - for paired pulse TMS applications, with the possibility to upgrade this system further into the DuoMAG MP-Quad, designed specifically for groundbreaking quadripulse stimulation.

Designed Specifically for Monophasic TMS

The DuoMAG MP system has been designed specifically to offer optimal performance for even the most demanding research applications using monophasic transcranial magnetic stimulation. Find out more about the various types of TMS here.

Compatible with a Range of Complementary Technologies

The DuoMAG MP integrates seamlessly with several other technologies from the Brainbox catalogue, including neuronavigation systems such as the Brainsight TMS Navigation system, TruScan Research EEG, Axilum TMS Robot and much more. For full information on compatibility with other systems, please get in touch with our team.

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Numerous Configurations

DuoMAG MP MagCartThe DuoMAG MP can be configured in a way to suit all budgets and workspaces. The system can be delivered as a simple desktop setup for those who wish to deliver single pulse TMS pulses; with a proprietary cart device for situations where the stimulator may need to be moved often; and can be supplied with a touchscreen interface and MEP module to record all participant EMG responses, depending on the requirements of each researcher's requirements.

The modular design of the system also provides users with the option to 'upgrade' their system in future to expand the stimulator's capabilities to paired pulse TMS or even quadripulse TMS.

MULTI-SYSTEM INTEGRATION

The system can be easily integrated with Deymed's clinical EMG and EEG amplifiers, allowing for multiple configurations of EMG/MEP or EEG signals to be displayed.

Easily Controllable

TMS Coil ControlsBuilt-in controls on the TMS coil handles allow the user to quickly adjust stimulator intensity without moving away from the subject and to deliver a TMS pulse with the touch of a button.

The system also features USB 2.0 and TTL ports, allowing users to easily interface the stimulator with other devices and equipment, or to control factors such as intensity or triggering through external systems such as Signal, MatLAB, or Python.

INTELLIGENT CHARGING ABILITIES

The DuoMAG MP makes use of new ultra-low capacitance induction charging technology from Deymed Diagnostic in order to guarantee the highest-quality EMG signal possible.

This technology makes the system suitable for sensitive neurophysiological tests, while also keeping the system's batteries at full charge.

CE-Certified

The DuoMAG MP system is a CE-certified medical device for non-invasive brain stimulation in humans. The device is limited to investigational and research use in the USA.

Pulse mode

Monophasic: single pulse

Max energy

700J (at 100%)

Max repetition rate at 100%

0.5Hz

Max repetition rate at 50%

1.4Hz

Max repetition rate

2.0Hz

Pulse width (rise/decay)

100µs / 1ms

Coil connections

1

Synchronisation

TTL in/out, via BNC
USB 2.0

Communication

USB or coil controls

Power supply

100-240Vac 50/60Hz

Dimensions

49cm x 19cm x 38cm

Weight

14.5kg

 

 

Graphical user interface

Optional

Trolley with coil holder

Optional

Upgrade options

MP-Dual, for paired pulse and twin coil TMS
MP-Quad, for quadripulse stimulation and low-frequency rTMS

 

 

EMG module (optional)

 

EMG channels

2 or 4, bipolar

Notch filter

50Hz and 60Hz (selectable)

Sampling rate

3kHz

Peak-to-peak measurement

Automatic

Latency measurement

Manual

Motor threshold tools

Resting (RMT)
Active (AMT)

  1. Dose-response of intermittent theta burst stimulation of the prefrontal cortex: a TMS-EEG study. Manon Desforges, Itay Hadas, Brian Mihov, Yan Morin, Mathilde Rochette, Braün, Pantelis Lioumis, Reza Zomorrodi, Hugo Théoret, Martin Lepage, Zafiris J.Daskalakis, SaraTremblay. Clinical Neurophysiology. January 2022
  2. A single, clinically relevant dose of the GABAB agonist baclofen impairs visuomotor learning. Ainslie Johnstone, Ioana Grigoras Pierre Petitet Liliana P. Capitão Charlotte J. Stagg. The Journal of Physiology. October 2020
  3. Failure of tDCS to modulate motor excitability and speech motor learning. Charlotte E.E. Wiltshire, Kate E.Watkins. Neuropsychologia. September 2020
  4. Motor imagery alone drives corticospinal excitability during concurrent action observation and motor imagery.. Meers R, Nuttall HE, & Vogt S.. Cortex. May 2020
  5. Primary visual cortex excitability is not atypical in acquired synaesthesia. Laura Lungu, Ryan Stewart, David P. Luke, & Devin B. Terhune. Brain Stimulation. April 2020
  6. Training load but not fatigue affects cross‐education of maximal voluntary force. David Colomer‐Poveda, Salvador Romero‐Arenas Juan Fariñas, Eliseo Iglesias‐Soler, Tibor Hortobágyi, Gonzalo Márquez. Scandinavian Journal of Medicine & Science in Sports. October 2020
  7. Investigation of Spatiotemporal Profiles of Single-Pulse TMS-Evoked Potentials with Active Stimulation Compared with a Novel Sham Condition. Mayuko Takano, Masataka Wada, Reza Zomorrodi, Keita Taniguchi, Xuemei Li, Shiori Honda, Yui Tobari, Yu Mimura, Shinichiro Nakajima, Ryosuke Kitahata, Masaru Mimura, Zafiris J. Daskalakis, Daniel M. Blumberger and Yoshihiro N. Biosensors. October 2022
  8. Dose-response of intermittent theta burst stimulation of the prefrontal cortex: A TMS-EEG study. Manon Desforges, Itay Hadas, Brian Mihov, Yan Morin, Mathilde Rochette Braün, Pantelis Lioumis, Reza Zomorrodi, Hugo Théoreta, Martin Lepaged, Zafiris J. Daskalakis, Sara Tremblay. Brain Stimulation. April 2022
  9. Reduced signal propagation elicited by frontal transcranial magnetic stimulation is associated with oligodendrocyte abnormalities in treatment-resistant depression. Masataka Wada, Shinichiro Nakajima, Shiori Honda, Mayuko Takano, Keita Taniguchi, Sakiko Tsugawa, Yu Mimura, Nanao Hattori, Shinsuke Koike, Reza Zomorrodi, Daniel M. Blumberger, Zafiris J. Daskalakis, Masaru Mimura and Yoshihiro Noda. Journal of Psychiatry & Neuroscience : JPN. September 2022

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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