DuoMAG MP-Quad TMS System

DuoMAG MP-Quad

The DuoMAG MP-Quad combines four DuoMAG MP stimulators to provide a powerful, fully configurable quadripulse (QPS) monophasic TMS system. The system can be used in full quadripulse stimulation mode, or alternatively as a single monophasic system or paired-pulse (ppTMS) stimulator.

DuoMAG MP-Quad

What is Quadripulse TMS?

Quadripulse* transcranial magnetic stimulation (QPS) is a novel method of repetitive transcranial magnetic stimulation (rTMS) that can be used to either increase or decrease cortical excitability in a subject.

The Power of Four Monophasic Stimulators

The DuoMAG MP-Quad system comprises four powerful DuoMAG MP monophasic stimulators, bundled with an additional, intelligent 'CombiBox' unit to allow for communication between the individual stimulators.

As well as delivering quadripulse stimulation, each DuoMAG MP unit that makes up the MP-Quad system is capable of being used as its own, independent monophasic system or as up to two paired-pulse (ppTMS) systems for the ultimate flexibility in research applications.

Additionally, where research conditions require the functionality, the DuoMAG MP-Quad is capable of delivering stimulation through four separate coils at the same time for interhemispheric (quadrilateral) stimulation.

Complete Freedom of Control Over Stimulation Parameters

When controlled via the native DuoMAG software, the DuoMAG MP-Quad is capable of delivering single-pulse TMS, paired-pulse TMS, defined QPS protocols and controlling all four stimulators separately to accomplish up to four coil stimulation for the investigation of inter-hemispheric stimulation.

The DuoMAG software provides intuitive, easy-to-use controls for a researcher, enabling full control of all stimulation parameters.

Stimulator outputs can all be set individually, or can even be combined to deliver pulses at up to 134% of a single stimulator's output through one TMS coil. Additionally, the inter-stimulus intervals (ISI) are configurable to a resolution as low as 0.1ms. The MP-Quad can be configured to allow for slow repetitive monophasic stimulation at up to 8Hz, with stimulation at 100% output as high as 2Hz.

USB 2.0 and TTL connections on the reverse of each stimulator allow for external control of individual stimulators and a programmable capacitor recharge delay can be utilised in instances of concurrent TMS-EEG studies.

QPS Rear

Universal DuoMAG Coil Compatibility

The DuoMAG MP-Quad is compatible with the full range of DuoMAG TMS coils, allowing the system to be used for any research application. All DuoMAG TMS coils feature built-in controls in the coil handle to remotely adjust stimulator intensity, as well as a button to trigger stimulation.

TMS Coil

*Quadripulse stimulation is sometimes alternatively referred to as 'Quadropulse' TMS by researchers.

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FULLY PROGRAMMABLE PROTOCOLS

The DuoMAG MP quad can be programmed via the proprietary DuoMAG software and computer interface, or controlled externally via programmes such as Python, Matlab and Signal. Quadripulse stimulation protocols with ISI intervals from 1ms - 800ms and IQI from 500ms. Configurable intensities for each stimulus in a train and a stimulation frequency of up to 8Hz is possible.

FULLY PROGRAMMABLE QPS

Programme ISI from 1ms to 800ms, and IQI from 500ms (2s at max. output). Configurable intensity for each A, B, C, and D stimulus. Up to 8Hz continuous repetition rate (2Hz at max. output).

MODULAR DESIGN

By joining four DuoMAG MP stimulators through the specially designed combining module, the MP-Quad is a highly flexible research tool, capable of being used as four separate single pulse stimulators, two paired pulse stimulators or a full quadripulse system. Talk to one of our product specialists about expanding your system today.

UNIVERSAL COIL COMPATIBILITY

Standardised coil connectors mean full coil compatibility across the whole range of Deymed Stimulators, all equipped with built in controls for stimulation and intensity settings. Air-Cooled and Liquid-Cooled coils allow the researcher to run higher intensity protocols for longer. Each coil has an inbuilt temperature gauge which will automatically halt stimulation when necessary.

Stimulation mode	Single Pulse	Paired Pulse	Quadripulse
Pulse shape	Monophasic
Pulse width (rise/decay)	100, 120µs / 1.0, 1.2ms
Max energy	700J (at 100%)
Max repetition rate at 100%	2.0Hz	1.0Hz	0.5Hz
Max repetition rate at 50%	5.6Hz	2.8Hz	1.4Hz
Max repetition rate	8.0Hz	4.0Hz	2.0Hz
Inter stimulus interval (ISI)	n/a	≥1.0ms	≥1.0ms
Coil connections	up to 4	up to 2	1
Synchronisation	TTL in/out, via BNC USB 2.0
Communication	USB or coil controls
Power supply	4 x (100-240Vac 50/60Hz)
Dimensions	4 x (49cm x 19cm x 38cm)
Weight	60kg

Graphical user interface	Optional
Trolley with coil holder	Optional

Brainsight targeting using MNI coordinates Video Tutorial: This tutorial will outline how to create a trajectory centred on parietal cortex using MNI co-ordinates from a previously completed experiment.

Compatible Products

This product can be used in combination with some of our other systems. Find out more by selecting one from the list below.

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Visit our shop to purchase accessories, consumables, and starter kits for this system

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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