The DuoMAG XT is a powerful, flexible repetitive transcranial magnetic stimulator built for ease of use in both research and clinical scenarios.

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What is Repetitive Transcranial Magnetic Stimulation (rTMS)?

Repetitive transcranial magnetic stimulation (rTMS), delivered by the DuoMAG XT rTMS system, can be applied to increase or decrease the excitability of the corticospinal tract depending on the intensity of stimulation, coil orientation, and frequency.

DuoMAG XT, for rTMS Applications

Available in three different iterations and a multitude of different configurations, the DuoMAG XT is the flagship rTMS device available from Brainbox.

With a focus on user-friendliness, the system's proprietary software houses a powerful 5kHz EMG software for the recording and analysis of MEPs. Patient data and session history can be saved, exported and anonymised, and a purpose-built TMS protocol builder enables allows for the simple creation of rTMS trains and theta burst protocols for both research and clinical applications.

The range-topping DuoMAG XT100 is capable of delivering 100Hz stimulation at 40% stimulator output and theta burst at 67% stimulator output. DuoMAG XT35 and XT10 stimulators are capable of delivering rTMS at 35Hz and 10Hz respectively.

Brainbox understands the need for flexible solutions within the workspace, and so is proud to offer the DuoMAG XT in three different configurations. A desktop set-up can be requested for laboratories without the available space for a cart. For those who’d prefer a more portable solution, the DuoMAG TMS cart with coil arm allows the stimulator and optional touchscreen computer to be moved easily between sites. Finally, popular in clinical institutions is the counterbalanced, electromagnetically-operated coil arm, designed specifically to help keep the coil position stable during longer rTMS sessions.

DuoMAG XT Configurations

All DuoMAG XT stimulators can be controlled externally via TTL, USB 2.0 or via ethernet connection for flexible research applications.

All DuoMAG systems also offer complete control over stimulator intensity and triggering via the built-in controls located on the coil handles (pictured below).

coil controls

Clinical Applications of rTMS

Repetitive TMS has been used in a number of clinical applications and rigorous studies in the past several years. Research using rTMS protocols has suggested that rTMS can be effective in the treatment of a number of neurological and psychiatric diseases including:

  • Depression
  • Parkinson's Disease
  • Epilepsy
  • Movement Disorders
  • Chronic pain and migraine
  • Tinnitus

An overview of the clinical applications of rTMS can be found in this journal reference.

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Intuitive software allows for the easy control of subject database, including fully anonymising data and exporting stimulation history. A dedicated screen for the calculation of resting motor threshold (RMT) and active motor threshold (AMT), with the ability to add/edit cursors to highlight amplitude/latency.

The DuoMAG XT's custom protocol editor enables the customisation of all stimulation parameters, including repetitive trains, stimulation frequency, burst frequency, and stimulation at a percentage of motor threshold. 


Following the delivery of a TMS pulse in single pulse mode, the DuoMAG EMG software is configured to record and plot the highest and lowest peaks of the resulting motor evoked potential (MEP). Latency information can be added, together with manipulation of the cursors where necessary.

MEP data is stored and used for the calculation of stimulator intensity when delivering repetitive TMS (rTMS) protocols.

All MEP data and information can be exported in multiple formats for offline analysis.


When calculating an active motor threshold (AMT), it is first necessary to record the participant's maximum voluntary isometric contraction (MVIC) before performing a contraction to a target percentage of this value.

A built-in feature of the DuoMAG software enables the researcher to calibrate both of these responses, and record active motor threshold values, while displaying a colour-coded target value for the participant.


External communications supported via TTL in/out triggers and USB.


The DuoMAG XT rTMS system offers seamless integration through the whole family of Deymed products for true multimodal research studies. Deymed EEG, EMG/MEP systems can control intensity and triggering of TMS devices enabling the user to maintain focus and attention on the participant, rather than the hardware.


Three different repetitive stimulator options and two different cart options enable us to specify a system to any budget or requirement. Standalone systems can be used for desktop workspaces, a cart enables the system to be mounted on a trolley and be portable for use in different sites and an optional counterbalanced electromagnetically operated arm can be specified to ensure coil movement is eliminated in a session. This flexibility, coupled with a wide range of coil types makes the DuoMAG systems unrivalled in terms of their customisation.


The DuoMAG XT rTMS system is a CE-certified medical device for non-invasive brain stimulation in humans. It is limited to investigational and research use in the USA.





Stimulation modes

Single pulse and repetitive

Single pulse, repetitive and burst

Single pulse, repetitive and burst

Pulse shape




Pulse width




Max energy

265J (optionally 320J)



Max repetition rate at 100%




Max repetition rate at 50%




Max repetition rate




Max frequency





TTL in/out, via BNC
USB 2.0




USB or coil controls



Power supply

100-240Vac 50/60Hz




49cm x 38cm x 16cm











Graphical user interface




Trolley with coil holder




Electromagnetic coil arm








EMG module




EMG channels

2 or 4, bipolar



Notch filter

50Hz and 60Hz (selectable)



Sampling rate




Peak-to-peak amplitude measurement




Latency measurement




Motor threshold tools

Resting (RMT)
Active (AMT)







GUI features




Patient detail entry




Programmable trains




Store/load protocols




Store/load MEPs




Change power within train




Data export




  1. Is the vertex a good control stimulation site? Theta burst stimulation in healthy controls. Dominik Pizem, Lubomira Novakova, Martin Gajdos & Irena Rektorova. Journal of Neural Transmission. 25/01/2022
  2. Hebbian Activity-Dependent Plasticity in White Matter. Lazari, A., Salvan, P., Cottaar, M., Papp. D., Rushworth, M., and Johansen-Berg, H. Cell Reports. December 2021
  3. Prefrontal stimulation prior to motor sequence learning alters multivoxel patterns in the striatum and the hippocampus. Mareike A. Gann, Bradley R. King, Nina Dolfen, Menno P. Veldman, Marco Davare, Stephan P. Swinnen, Dante Mantini, Edwin M. Robertson & Geneviève Albouy. Scientific Reports. October 2021
  4. Functional Connectivity at Rest between the Human Medial Posterior Parietal Cortex and the Primary Motor Cortex Detected by Paired-Pulse Transcranial Magnetic Stimulation. Rossella Breveglieri, Sara Borgomaneri, Matteo Filippini, Marina De Vitis, Alessia Tessari, Patrizia Fattori. Brain Sciences. October 2021
  5. Development of an Advanced Sham Coil for Transcranial Magnetic Stimulation and Examination of Its Specifications. Mayuko Takano, Jiri Havlicek, Dan Phillips, Shinichiro Nakajima, Masaru Mimura, and Yoshihiro Noda. Journal of Personalized Medicine. October 2021
  6. Seizure risk with repetitive TMS: Survey results from over a half-million treatment sessions.. Joseph J. Taylor, Noam G. Newberger, Adam P. Stern, Angela Phillips, David Feifel, Rebecca, A. Betensky, Daniel Z. Press. Brain Stimulation. August 2021
  7. Impact of one HF-rTMS session over the DLPFC and motor cortex on acute hormone dynamics and emotional state in healthy adults: a sham-controlled pilot study. Blair T. Crewther, Wiktoria Kasprzycka, Christian J. Cook & Rafał Rola. Neurological Sciences. May 2021
  8. Prefrontal stimulation prior to motor sequence learning alters multivoxel patterns in the striatum and the hippocampus. Mareike Gann, Bradley King, Nina Dolfen, Menno Veldman, Marco Davare, Stephen Swinnen, Dante Mantini, Edwin Robertson & Genevieve Albouy. Neuroimage. May 2021
  9. Low-frequency rTMS to the parietal lobe increases eye-movement carryover and decreases hazard rating. P.J. Hills, G. Arabaci, J. Fagg, C. Thompson & R. Moseley. Neuropsychologia. May 2021
  10. Short-Term Immobilization Promotes a Rapid Loss of Motor Evoked Potentials and Strength That Is Not Rescued by rTMS Treatment. Christopher Gaffney, Amber Drinkwater, Shalmali Joshi, Brandon O’Hanlon, Abbie Robinson, Kayle-Anne Sands, Kate Slade, Jason Braithwaite and Helen Nuttall. Frontiers in Human Neuroscience. April 2021
  11. Natural oscillation frequencies in the two lateral prefrontal cortices induced by Transcranial Magnetic Stimulation. Antonino Vallesi, Alessandra Del Felice, Mariagrazi Capizzi, Alessandra Tafuro, Emanuela Formaggio, Patrizia Bisiacchi, Stefano Masiero, Ettore Ambrosini. Neuroimage. February 2021
  12. Motor resonance is modulated by an object’s weight distribution. Guy Rens, Jean-Jacques Orban de Xivry, Marco Davare, Vonne van Polanen. Neuropsychologia. 2021
  13. Identification of psychiatric disorder subtypes from functional connectivity patterns in resting-state electroencephalography. Yu Zhang, Wei Wu, Russell T. Toll, Sharon Naparstek, Adi Maron-Katz, Mallissa Watts, Joseph Gordon, Jisoo Jeong, Laura Astolfi, Emmanuel Shpigel, Parker Longwell, Kamron Sarhadi, Dawlat El-Said, Yuanqing Li, Crystal Cooper, Cherise Chin-Fatt, Martijn Arns. Nature Biomedical Engineering. October 2020
  14. Enhancing cognitive training effects in Alzheimer’s disease: rTMS as an add-on treatment. Bagattini Chiara, Zanni Mara, Barocco Federica, Caffarra Paolo, Brignani Debora, Miniussi Carlo, Defanti Carlo Alberto. Brain Stimulation. September 2020
  15. The role of the anterior intraparietal sulcus and the lateral occipital cortex in fingertip force scaling and weight perception during object lifting. Vonne van Polanen, Guy Rens, and Marco Davare. Journal of Neurophysiology. August 2020
  16. Sensorimotor expectations bias motor resonance during observation of object lifting: The causal role of pSTS. Guy Rens, Vonne van Polanen, Alessandro Botta, Mareike A. Gann, Jean-Jacques Orban de Xivry and Marco Davare. Journal of Neuroscience, JN-RM-2672-19. April 2020
  17. An electroencephalographic signature predicts antidepressant response in major depression. Wei Wu, Yu Zhang, […] Amit Etkin. Nature Biotechnology. February 2020
  18. Theta-burst transcranial magnetic stimulation induced cognitive task-related decrease in activity of default mode network: An exploratory study. Lubomira Novakova, Martin Gajdos, & Irena Rektorova. Brain Stimulation. January 2020
  19. The role of the anterior intraparietal sulcus and the lateral occipital cortex in fingertip force scaling and weight perception during object lifting. Vonne van Polanen, Guy Rens, & Marco Davare. bioRxiv. December 2019
  20. Restoring tactile sensations via neural interfaces for real-time force-and-slippage closed-loop control of bionic hands. Loredana Zollo, Giovanni Di Pino, Anna L. Ciancio, Federico Ranieri, Francesca Cordella, Cosimo Gentile, Emiliano Noce, Rocco A. Romeo, Alberto Dellacasa Bellingegni, Gianluca Vadalà, Sandra Miccinilli, Alessandro Mioli [...] and Eugenio Guglielmelli. Science Robotics. February 2019
  21. Non-invasive stimulation of the auditory feedback area for improved articulation in Parkinson's disease. Lubos Brabenec, Patricia Klobusiakova, Marek Barton, Jiri Mekysk, Zoltan Galaz, Vojtech Zvoncak, Tomas Kiska, Jan Mucha, Zdenek Smekal, Milena Kostalova, & Irena Rektorova. Parkinsonism & Related Disorders. October 2018
  22. Intermittent Theta Burst Stimulation Over Ventral Premotor Cortex or Inferior Parietal Lobule Does Not Enhance the Rubber Hand Illusion. Alessandro Mioli, Marco D’Alonzo, Giovanni Pellegrino, Domenico Formica, and Giovanni Di Pino. Frontiers in Neuroscience. 2018
  23. Combining Robotic Training and Non-Invasive Brain Stimulation in Severe Upper Limb-Impaired Chronic Stroke Patients. Vincenzo Di Lazzaro, Fioravante Capone, Giovanni Di Pino, Giovanni Pellegrino, Lucia Florio, Loredana Zollo, Davide Simonetti, Federico Ranieri, Nicoletta Brunelli, Marzia Corbetto, Sandra Miccinilli, Marco Bravi, & Stefano Milighet. Frontiers in Neuroscience. October 2016
  24. Recognition and Processing of Visual Information after Neuronavigated Transcranial Magnetic Stimulation Session. Wiktoria Kasprzycka, Magdalena Ligia Naurecka, Bartosz Michał Sierakowski, Paulina Putko, Zygmunt Mierczyk, Grzegorz Chabik, Stanisław Dec, Stefan Gaździński and Rafał Rola. Brain Sciences. September 2022

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Grant Applications, Industrial Projects, Workshops

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