DuoMAG XT

The DuoMAG XT is a powerful, flexible repetitive transcranial magnetic stimulator built for ease of use in both research and clinical scenarios.

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DuoMag XT

DuoMAG XT

Repetitive transcranial magnetic stimulation (rTMS), delivered by the DuoMAG XT rTMS system, can be applied to increase or decrease the excitability of the corticospinal tract depending on the intensity of stimulation, coil orientation, and frequency.

Available in three different iterations and a multitude of different configurations, the DuoMAG XT is the flagship rTMS device available from Brainbox. With a focus on user-friendliness, proprietary software houses a powerful 5kHz EMG software for the recording and analysis of MEP’s, patient data and session history can be saved, exported and anonymised, and a purpose built protocol builder enables allows for the simple creation of rTMS trains and theta burst protocols for both research and clinical applications.

The range topping DuoMAG XT100 is capable of delivering 100Hz stimulation at 40% stimulator output and theta burst at 67% stimulator output. DuoMAG XT35 and XT10 stimulators are capable of delivering rTMS at 35Hz and 10Hz respectively.

Brainbox understand the need for flexible solutions within the workspace, and so are proud to offer the DuoMAG XT in three different configurations. A desktop set up can be requested for laboratories without the available space for cart, for those who’d prefer a more portable solution, the DuoMAG TMS cart with coil arm allows the stimulator and optional touchscreen computer to be moved easily between sites. Finally, popular in clinical institutions is the counterbalanced electromagnetically operated coil arm, keeping the coil position stable during longer rTMS sessions.

All DuoMAG XT stimulators can be controlled externally via TTL, USB 2.0 or via ethernet connection for flexible research applications.

CUSTOM PROTOCOL EDITOR

Intuitive software allows for the easy control of subject database, including fully anonymising data and exporting stimulation history. A dedicated screen for the calculation of resting motor threshold (RMT) and active motor threshold (AMT), with the ability to add/edit cursors to highlight amplitude/latency.

The DuoMAG XT's custom protocol editor enables the customisation of all stimulation parameters, including repetitive trains, stimulation frequency, burst frequency, and stimulation at a percentage of motor threshold. 

AUTOMATIC MEP AMPLITUDE CALCULATION

Following the delivery of a TMS pulse in single pulse mode, the DuoMAG EMG software is configured to record and plot the highest and lowest peaks of the resulting motor evoked potential (MEP). Latency information can be added, together with manipulation of the cursors where necessary.

MEP data is stored and used for the calculation of stimulator intensity when delivering repetitive TMS (rTMS) protocols.

All MEP data and information can be exported in multiple formats for offline analysis.

ACTIVE MOTOR THRESHOLD CALCULATION

When calculating an active motor threshold (AMT), it is first necessary to record the participant's maximum voluntary isometric contraction (MVIC) before performing a contraction to a target percentage of this value.

A built-in feature of the DuoMAG software enables the researcher to calibrate both of these responses, and record active motor threshold values, while displaying a colour-coded target value for the participant.

EXTERNAL COMMUNICATIONS

External communications supported via TTL in/out triggers and USB.

MULTIMODAL APPLICATIONS

The DuoMAG XT rTMS system offers seamless integration through the whole family of Deymed products for true multimodal research studies. Deymed EEG, EMG/MEP systems can control intensity and triggering of TMS devices enabling the user to maintain focus and attention on the participant, rather than the hardware.

MULTIPLE CONFIGURATIONS

Three different repetitive stimulator options and two different cart options enable us to specify a system to any budget or requirement. Standalone systems can be used for desktop workspaces, a cart enables the system to be mounted on a trolley and be portable for use in different sites and an optional counterbalanced electromagnetically operated arm can be specified to ensure coil movement is eliminated in a session. This flexibility, coupled with a wide range of coil types makes the DuoMAG systems unrivalled in terms of their customisation.

CE-CERTIFICATION

The DuoMAG XT rTMS system is a CE-certified medical device for non-invasive brain stimulation in humans. It is limited to investigational and research use in the USA.

 

XT-10

XT-35

XT-100

Stimulation modes

Single pulse and repetitive

Single pulse, repetitive and burst

Single pulse, repetitive and burst

Pulse shape

Biphasic

 

 

Pulse width

290µs

 

 

Max energy

265J (optionally 320J)

 

 

Max repetition rate at 100%

5Hz

13Hz

22Hz

Max repetition rate at 50%

10Hz

35Hz

86Hz

Max repetition rate

10Hz

35Hz

100Hz

Max frequency

10Hz

35Hz

100Hz

Synchronisation

TTL in/out, via BNC
USB 2.0

 

 

Communication

USB or coil controls

 

 

Power supply

100-240Vac 50/60Hz

 

 

Dimensions

49cm x 38cm x 16cm

 

 

Weight

15kg

 

 

 

 

 

 

Graphical user interface

Included

 

 

Trolley with coil holder

Included

 

 

Electromagnetic coil arm

Optional

 

 

 

 

 

 

EMG module

 

 

 

EMG channels

2 or 4, bipolar

 

 

Notch filter

50Hz and 60Hz (selectable)

 

 

Sampling rate

3kHz

 

 

Peak-to-peak amplitude measurement

Automatic

 

 

Latency measurement

Manual

 

 

Motor threshold tools

Resting (RMT)
Active (AMT)

 

 

 

 

 

 

GUI features

 

 

 

Patient detail entry

Yes

 

 

Programmable trains

Yes

 

 

Store/load protocols

Yes

 

 

Store/load MEPs

Yes

 

 

Change power within train

Yes

 

 

Data export

Yes

 

 

  1. Identification of psychiatric disorder subtypes from functional connectivity patterns in resting-state electroencephalography. Yu Zhang, Wei Wu, Russell T. Toll, Sharon Naparstek, Adi Maron-Katz, Mallissa Watts, Joseph Gordon, Jisoo Jeong, Laura Astolfi, Emmanuel Shpigel, Parker Longwell, Kamron Sarhadi, Dawlat El-Said, Yuanqing Li, Crystal Cooper, Cherise Chin-Fatt, Martijn Arns. Nature Biomedical Engineering. October 2020
  2. Enhancing cognitive training effects in Alzheimer’s disease: rTMS as an add-on treatment. Bagattini Chiara, Zanni Mara, Barocco Federica, Caffarra Paolo, Brignani Debora, Miniussi Carlo, Defanti Carlo Alberto. Brain Stimulation. September 2020
  3. The role of the anterior intraparietal sulcus and the lateral occipital cortex in fingertip force scaling and weight perception during object lifting. Vonne van Polanen, Guy Rens, and Marco Davare. Journal of Neurophysiology. August 2020
  4. Sensorimotor expectations bias motor resonance during observation of object lifting: The causal role of pSTS. Guy Rens, Vonne van Polanen, Alessandro Botta, Mareike A. Gann, Jean-Jacques Orban de Xivry and Marco Davare. Journal of Neuroscience, JN-RM-2672-19. April 2020
  5. An electroencephalographic signature predicts antidepressant response in major depression. Wei Wu, Yu Zhang, […] Amit Etkin. Nature Biotechnology. February 2020
  6. Theta-burst transcranial magnetic stimulation induced cognitive task-related decrease in activity of default mode network: An exploratory study. Lubomira Novakova, Martin Gajdos, & Irena Rektorova. Brain Stimulation. January 2020
  7. The role of the anterior intraparietal sulcus and the lateral occipital cortex in fingertip force scaling and weight perception during object lifting. Vonne van Polanen, Guy Rens, & Marco Davare. bioRxiv. December 2019
  8. Restoring tactile sensations via neural interfaces for real-time force-and-slippage closed-loop control of bionic hands. Loredana Zollo, Giovanni Di Pino, Anna L. Ciancio, Federico Ranieri, Francesca Cordella, Cosimo Gentile, Emiliano Noce, Rocco A. Romeo, Alberto Dellacasa Bellingegni, Gianluca Vadalà, Sandra Miccinilli, Alessandro Mioli [...] and Eugenio Guglielmelli. Science Robotics. February 2019
  9. Non-invasive stimulation of the auditory feedback area for improved articulation in Parkinson's disease. Lubos Brabenec, Patricia Klobusiakova, Marek Barton, Jiri Mekysk, Zoltan Galaz, Vojtech Zvoncak, Tomas Kiska, Jan Mucha, Zdenek Smekal, Milena Kostalova, & Irena Rektorova. Parkinsonism & Related Disorders. October 2018
  10. Intermittent Theta Burst Stimulation Over Ventral Premotor Cortex or Inferior Parietal Lobule Does Not Enhance the Rubber Hand Illusion. Alessandro Mioli, Marco D’Alonzo, Giovanni Pellegrino, Domenico Formica, and Giovanni Di Pino. Frontiers in Neuroscience. 2018
  11. Combining Robotic Training and Non-Invasive Brain Stimulation in Severe Upper Limb-Impaired Chronic Stroke Patients. Vincenzo Di Lazzaro, Fioravante Capone, Giovanni Di Pino, Giovanni Pellegrino, Lucia Florio, Loredana Zollo, Davide Simonetti, Federico Ranieri, Nicoletta Brunelli, Marzia Corbetto, Sandra Miccinilli, Marco Bravi, & Stefano Milighet. Frontiers in Neuroscience. October 2016

Compatible Products

This product can be used in combination with some of our other systems. Find out more by selecting one from the list below.

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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