neuroConn DC-Stimulator PLUS

The neuroConn DC-Stimulator PLUS is a versatile transcranial electrical stimulator (tES) for non-invasive brain stimulation that offers precise, flexible control for all of your tDCS, tACS, and tRNS protocols.

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neuroConn DC-Stimulator PLUS

neuroConn DC-Stimulator PLUS

The neuroConn DC-Stimulator PLUS is one of the most well-established tES devices available, used in an extensive list of publications. In addition to standard features such as microprocessor-controlled constant current source, it also includes a range of advanced optional features such as double-blind sham control, analogue signal control, real-time signal output, and MRI compatibility. The range of options available makes the device highly configurable and suitable for a diverse array of applications.

The stimulator meets the highest safety standards thanks to multistage monitoring of the current path using both hardware and software. By means of continuously monitoring electrode impedance, the stimulator is able to accurately maintain the user-defined current amplitude while also automatically detecting if there is insufficient contact with the skin. It will automatically terminate stimulation to ensure subject safety.

The DC-Stimulator PLUS is not a medical device according to MDD93/42 EEC. The device is intended strictly for neuroscientific research.

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STUDY MODE FOR SHAM STIMULATION

For double-blind sham stimulation control, remember to add the Study Mode option to your system. This option allows the user to select a pre-defined stimulation protocol and depending on the 5-digit code entered by the operator, the current delivered will either follow the active stimulation waveform shape, or a pseudo stimulation output. In both cases, the stimulator display will show the same information during real and sham stimulation.

MRI-COMPATIBLE OPTION

An MRI-compatible upgrade is available for this system, which can be included at the time of purchase, or retrospectively added to your DC-Stimulator PLUS. The 'DC-Stimulator MR' is the most extensively used device for combined tES-MRI studies, due to its reliability in delivering artefact free stimulation during fMRI. It is suitable for use with 1.5T and 3T MRI scanners.

EEG COMPATIBILITY

With the addition of one of three 'Signal Output' options, the DC-Stimulator PLUS offers is well suited to integration with EEG. This features allows the stimulation waveform (amplitude, frequency, shape etc.) to be streamed directly to an EEG system, or other recording devices, in the form of an analogue signal. The recorded stimulation signal can then be used for online or offline artefact correction of the EEG data. The 'Signal Output' option can also be useful in applications where the stimulator output needs to be monitored by an external device; for example, to synchronise the onset of visual or other stimuli.

EXTERNAL STIMULATION CONTROL

Remote, online modulation of stimulation parameters is available with the addition of an analogue input 'Remote Option'. This is particularly useful for research applications where time-locked, synchronised and/or varying stimulation parameters are required; for example tES-EEG applications and dual-site tACS applications.

Number of Channels

1 pair (1 anode, 1 cathode)

Power Supply

Built-in, rechargeable battery

Operating Time

Approximately 6 hours

Stimulation Modes

tDCS, tACS, tRNS, Pulsed tDCS, Sinus (W), Sinus (HW), Analogue Input (optional)

Maximum Voltage

20V

Dimensions

135mm x 225mm x 55mm

Weight

0.8kg

 

 

tDCS Parameters

 

Stimulation Current

max. ±4.5mA (increment 25µA)

Stimulation Duration

15-1800s (increment 15s)

Fade In/Out

0-60s (increment 1s)

 

 

tACS Parameters

 

Stimulation Current (peak-to-peak)

max. 3mA (increment 25µA)

Offset

±1mA (increment 10µA)

Frequency

0.25-250Hz (increment 0.01Hz)

Number of Cycles

1-350000 (increment 1)

Fade In/Out Cycles

0-4500 (increment 1)

Maximum Duration

8 hours

  1. Neural mechanisms underlying the after-effects of repetitive paired-pulse TMS with β tACS on the human primary motor cortex. Nakazono, H., Ogata, K., Mitsutake, T., Takeda, A., Yamada, E., & Tobimatsu, S. (2025). Scientific Reports, 15(1), 7286.
  2. Alpha modulation via transcranial alternating current stimulation in adults with attention-deficit hyperactivity disorder. Kannen, K., Rasbach, J., Fantazi, A., Wiebe, A., Selaskowski, B., Asché, L., Aslan, B., Lux, S., Herrmann, C. S., Philipsen, A., & Braun, N. (2024). Frontiers in Psychology, 14.
  3. Transcranial direct current stimulation over the right intraparietal sulcus improves response inhibition. Shiga, K., Miyaguchi, S., Inukai, Y., Otsuru, N., & Onishi, H. (2023). Behavioural Brain Research, 437, 114110.
  4. A differential effect of visual cortex tDCS on reading of English and Chinese in patients with central vision loss. Silva, A. E., Lyu, A., Leat, S. J., Khan, S., Labreche, T., Chan, J. C. H., Li, Q., Woo, G. C., Woo, S., Cheong, A. M. Y., & Thompson, B. (2022). Brain Stimulation: Basic, Translational, and Clinical Research in Neuromodulation, 15(5), 1215–1217.
  5. P300 Modulation via Transcranial Alternating Current Stimulation in Adult Attention-Deficit/Hyperactivity Disorder: A Crossover Study. Kannen, K., Aslan, B., Boetzel, C., Herrmann, C. S., Lux, S., Rosen, H., Selaskowski, B., Wiebe, A., Philipsen, A., & Braun, N. (2022). Frontiers in Psychiatry, 13.
  6. Transcranial Pulsed-Current Stimulation versus Transcranial Direct Current Stimulation in Patients with Disorders of Consciousness: A Pilot, Sham-Controlled Cross-Over Double-Blind Study. Barra, A., Rosenfelder, M., Mortaheb, S., Carrière, M., Martens, G., Bodien, Y. G., Morales-Quezada, L., Bender, A., Laureys, S., Thibaut, A., & Fregni, F. (2022). Brain Sciences, 12(4), 429.
  7. Effects of Transcranial Direct Current Stimulation of Bilateral Supplementary Motor Area on the Lower Limb Motor Function in a Stroke Patient with Severe Motor Paralysis: A Case Study. Ohnishi, S., Mizuta, N., Hasui, N., Taguchi, J., Nakatani, T., & Morioka, S. (2022). Brain Sciences, 12(4), 452.
  8. Combining transcranial direct current stimulation and peripheral electrical stimulation to improve upper limb function in a patient with acute central cord syndrome: A case report. Matsuo, H., Kubota, M., Hori, Y., Izubuchi, Y., Takahashi, A., Watanabe, S., Nakajima, H., & Matsumine, A. (2022). Journal of International Medical Research, 50(3), 03000605221083248.
  9. Double-blind, randomized pilot clinical trial targeting alpha oscillations with transcranial alternating current stimulation (tACS) for the treatment of major depressive disorder (MDD). Alexander, M. L., Alagapan, S., Lugo, C. E., Mellin, J. M., Lustenberger, C., Rubinow, D. R., & Fröhlich, F. (2019). Translational Psychiatry, 9(1), 106.
  10. tDCS-induced episodic memory enhancement and its association with functional network coupling in older adults. Antonenko, D., Hayek, D., Netzband, J., Grittner, U., & Flöel, A. (2019). Scientific Reports, 9(1), 2273.

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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