NeuroFUS PRO

The NeuroFUS PRO system is a complete, laboratory-ready system that can be used to administer low-intensity, pulsed transcranial ultrasound stimulation (TUS/tFUS/FUS) to the brain. 

What is Transcranial Ultrasound Stimulation?

Transcranial ultrasound stimulation (sometimes referred to as Transcranial-focused ultrasound stimulation and Transcranial-focused ultrasound neuromodulation) is a non-invasive means of brain stimulation that uses low-intensity sound waves (ultrasound) to temporarily affect or alter brain activity in a subject.

TUS offers unprecedented spatial resolution and depth of focus versus other methods of non-invasive brain stimulation - such as TMS, tES, or DBS - and has been shown to be a safe and effective method of delivering precise ultrasonic energy to the brain without causing tissue damage or lasting neurological effects.

Read a full introduction to Transcranial-focused ultrasound stimulation here.

A demonstration of the NeuroFUS system in action:

What can NeuroFUS offer my research?

The NeuroFUS PRO delivers transcranial (tFUS/TUS) or peripheral-focused ultrasound (pFUS) waveforms for the modulation of neuronal activity at a high resolution. Transcranial- ultrasound stimulation works in a similar way to transcranial magnetic stimulation (TMS) but uses low-intensity pulsed ultrasound (LIFU) in place of magnetic pulses. As a result, NeuroFUS offers significantly higher spatial resolution and is capable of reaching deeper brain regions vs other methods of non-invasive brain stimulation. 

Ultimate Flexibility in Study Design

The NeuroFUS PRO system is electromagnetically and mechanically compatible with an extensive range of modern neuroscience research methods and neurotechnologies, including:

• Human behaviour;
• Optical imaging (including techniques such as fNIRS);
• Electroencephalography (EEG);
• Augmented Reality and/or Virtual Reality immersion/stimulation;
• Peripheral nerve stimulation (including Vagus Nerve Stimulation (VNS));
• Brain-computer interfaces (BCIs);
• Computational modelling techniques;
• and other traditional neuromodulation methods such as tES, tDCS, tACS, and TMS.

NeuroFUS' integration with a wide range of complementary technologies offers researchers the possibility of carrying out truly advanced multimodal neuroscience projects.

The NeuroFUS is intended as a TUS/FUS research system and has not yet been certified as a medical device.

What is Transcranial Focused Ultrasound Neuromodulation?

Transcranial-focused ultrasound is an innovative new form of neuromodulation that uses low-intensity sound waves to temporarily affect or alter brain activity.

TUS offers unprecedented spatial resolution and depth of focus versus other methods of non-invasive brain stimulation (such as TMS, tES, or DBS), and has been shown to be a safe and effective method of delivering precise ultrasonic energy to the brain without causing tissue damage or lasting neurological effects.

An Introduction to Transcranial Ultrasound Stimulation:

Dr Lennart Verhagen (Donders Institute) provides an introduction to TUS research techniques in this Brainbox Initiative webinar.