Neurophet tES Lab

Neurophet tES Lab 4.0 is a complete, powerful transcranial electrical stimulation computational modelling and simulation software that allows users to calculate and visualise brain stimulation effects based on individual brain structure and stimulus conditions.

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Neurophet tES Lab

Neurophet tES Lab

Ultra-fast Brain Segmentation

The sophisticated AI engine behind Neurophet tES Lab 4.0 is capable of carrying out fully-automated, ultra-fast brain segmentation of a subject's individual magnetic resonance imaging (MRI) data, significantly shortening the time required to carry out a process that can take multiple hours with other methods. With Neurophet tES Lab, users are able to quickly simulate all tissues that separate tES electrodes from the brain, such as skin, skull, CSF, white matter, and grey matter.

Based on this MRI data segmentation, the advanced built-in brain modelling engine is then capable of creating a fully-personalised, 3D individual brain model that can be used to simulate current flow, which can increase accuracy in positioning electrodes and potentially lead to less variable, more reproducible tES effects.

Computational Modelling Without MRI Data

For researchers working without MRI data, the Neurophet software also includes a wide variety of human templates, from stock MRI data to fully-rendered 3D models for a rich and fast, easily accessible research environment.

User-friendly Controls

Neurophet tES Lab 4.0’s intuitive interface can calculate the best configuration of electrodes to apply focal stimulation to a desired target, in addition to simulating current flow from user-defined montages (including 10-20 co-ordinate positioning).

The software's easy-to-use interface, controls, and flexible settings allow users to modify and adapt all aspects of their desired tES protocol. Neurophet tES Lab offers researchers full control over the size, shape (circle, square, ring, etc.), number, position, and intensity (mV) of all electrodes, as well as control over waveform type (tDCS/tACS) with just a few clicks.

Neurophet tES Lab Graphical User Interface for Current Flow Modelling


Simulated stimulation results allow users to view the effects of the applied stimulation and analyse these findings in a number of ways, including user-selected points on a segmented MRI.

For ultimate compatibility with other experiments, Neurophet tES Lab supports the export of 3D models and simulated stimulation result data for use in collaboration with other studies in a variety of common formats (MATLAB, Python, etc.).

View an Introduction to the Neurophet tES Lab 2.0

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USER FRIENDLY OPERATION

Neurophet tES Lab Graphical User InterfaceWhereas some solutions for computational modelling techniques require users to have a deep understanding of complex coding techniques, the Neurophet tES Lab's user-friendly UI and ultra-fast, responsive operation provides the ultimate ease-of-use for any tES researchers looking to try current flow modelling for themselves.

AUTOMATIC SEGMENTATION

Automatic Segmentation with Neurophet tES LabThe Neurophet tES Lab offers full, automatic segmentation of imported MRI data. With Neurophet tES Lab, users are able to quickly simulate all tissues that separate tES electrodes from the brain, such as skin, skull, CSF, white matter, and grey matter.

MRI DATA COMPATIBILITY

Convert MRI data to 3D Models for Computational ModellingThe Neurophet tES Lab allows users to import a subject's individual MRI data to create a fully 3D render of the subject's head.

For those working without individual MRI data, Neurophet offers a large bank of preset human templates.

FULL ELECTRODE CUSTOMISATION

Neurophet tES Lab offers full customisation of electrodesNeurophet tES Lab offers researchers full freedom to customise electrodes. Round, square, and ring electrodes can be created in a range of various sizes.

SIMULATE & ANALYSE STIMULATION

Simulate & analyse the potential effects of tESNeurophet tES Lab allows researchers to quickly optimise, simulate and analyse the effects of stimulation to their chosen brain regions. 

Various colour maps allow users to easily customise and change their settings for ultimate accessibility.

ROBUST DATA EXPORT OPTIONS

Neurophet tES Lab Offers Multiple Export OptionsThe Neurophet tES Lab offers robust data export options.

3D models and stimulation results can be exported for use and compatibility with other studies run in MATLAB and Python.

Format

NIfTI-1(.nii)

 

 

Sequence

T1-weighted

 

 

Slice spacing

Coronal ≤ 1.0 mm

Sagittal ≤1.0 mm

Axial ≤1.6 mm

Field strength

1.5T

3.0T

 

Validated MRI data

GE

SPGR

Singha HDxt 1.5T

 

Philips

MPRAGE

Intre 1.5T

 

 

TFE

Ingenia 3T

 

 

 

Intra 3T

 

Siemens

MPRAGE

Skyra 3T

 

 

 

Verio 3T

  1. Non-invasive electrical brain stimulation modulates human conscious perception of mental representation. Seo, J., & Min, B.-K. (2024). NeuroImage, 294, 120647.
  2. Impact of Electric Field Magnitude in the Left Dorsolateral Prefrontal Cortex on Changes in Intrinsic Functional Connectivity Using Transcranial Direct Current Stimulation: A Randomized Crossover Study. Kim, E., Yun, S. J., Oh, B.-M., & Seo, H. G. (2024). Journal of Neuroscience Research, 102(9), e25378.
  3. Electric field simulation and appropriate electrode positioning for optimized transcranial direct current stimulation of stroke patients: An in Silico model. Yoon, M.-J., Park, H. J., Yoo, Y. J., Oh, H. M., Im, S., Kim, T.-W., & Lim, S. H. (2024). Scientific Reports, 14(1), 2850.
  4. Effect of optimized transcranial direct current stimulation on motor cortex activation in patients with sub-acute or chronic stroke: A study protocol for a single-blinded cross-over randomized control trial. Kim, T., Salazar Fajardo, J. C., Jang, H., Lee, J., Kim, Y., Kim, G., & Kim, D. (2023). Frontiers in Neuroscience, 17.
  5. Left prefrontal transcranial direct-current stimulation reduces symptom-severity and acutely enhances working memory in schizophrenia. Meiron, O., David, J., & Yaniv, A. (2021). Neuroscience Letters, 755, 135912.
  6. Targeting reduced neural oscillations in patients with schizophrenia by transcranial alternating current stimulation. Ahn, S., Mellin, J. M., Alagapan, S., Alexander, M. L., Gilmore, J. H., Jarskog, L. F., & Fröhlich, F. (2019). NeuroImage, 186, 126–136.
  7. Geometrical Variation’s Influence on the Effects of Stimulation May be Important in the Conventional and Multi-Array tDCS–Comparison of Electrical Fields Computed. Im, C., Seo, H., & Jun, S. C. (2019). IEEE Access, 7, 8557–8569.

Compatible Products

This product can be used in combination with some of our other systems. Find out more by selecting one from the list below.

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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