nurostym tES

Nurostym tES is a complete solution for transcranial electrical stimulation (tES), offering tDCS, tACS, tRNS, pulsed tDCS, AM-tACS and Analogue Input stimulation modes. Nurostym tES offers complete flexibility in study design, as well as the ability to easily standardise study replication.

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DuoMag XT

nurostym tES

The nurostym is a powerful, complete tES device that offers complete control of stimulation parameters; fully programmable protocols; sham and double-blind controls; advanced safety functions; and user-friendly controls to enable even the most complex of studies using transcranial electrical stimulation.

Offering an intuitive and responsive touchscreen GUI, the nurostym enables quick, easy, and powerful customisation of all stimulation protocols directly from the device. The nurostym also integrates seamlessly with its proprietary computer application: a Windows program that allows the user to generate and save up to eight custom stimulation paradigms; remotely control the nurostym device through trigger-in and trigger-out connections; as well as providing access to stimulation logs and performing system software and firmware updates.

Nurostym includes state-of-the-art safety monitoring features as standard to ensure the wellbeing of both operator and subject. A multi-staged programmable impedance alarm and automatic 'Safe-stop' cutoff system are included as default both to provide the operator with a clear notification of increased impedance and to minimise discomfort to the subject. The nurostym hardware itself is limited to a maximum of 50kOhm to ensure safe operation at all times.

When setting up stimulation paradigms, the system offers the user the option to input the size of the electrodes being used for stimulation. The nurostym can then automatically perform a current density calculation and advise the researcher if the current due to be delivered my cause an uncomfortable sensation or adverse effects for the participant. For research use, the option to ignore electrode size is available.

The nurostym tES system comes complete with two accessories to increase its functionality: the nurostym INTERFACE (IO Box) and the nurostym SPLITTER.

nurostym SPLITTER

The nurostym INTERFACE (IO Box) features 7 BNC connections, a 15 pin D-Type connector, and three touchproof connections. 5 BNC ports are given to triggers—two in, three out—with the additional two providing the option for analogue connections.

nurostym SPLITTER

The nurostym SPLITTER accessory allows the user or researcher to make use of up to four return channels of stimulation through a single active channel. While users of typical tES devices would assume even distributions of current across four channels, the nurostym's inclusion of a dedicated switch for each channel means that users can accurately measure impedance levels for each channel separately.

In addition to these features, the nurostym also offers double-blinding (study mode) and sham control through the use of a five-digit numerical code to ensure that only the study manager is able to change the stimulation parameters.

Additional triggering modes (Easy mode and Complex Triggering) are also available. Through entering a device-specific PIN code, the nurostym can be loaded into 'Easy Mode', restricting the device to operation only in specific, predefined conditions. Using this, and under the strict guidance of a medical professional, the device may be configured into Easy Mode to allow for the operation of the nurostym in a home environment.

For more complex triggering options, the device's two trigger-in channels may be configured to start, stop, or both on the rising and falling edges of a pulse. Trigger-Out options are more numerous & complex. As well as being able to trigger on the High & Low levels of stimulation, the nurostym can send triggers out every time the polarity changes, any time the maximum and/or minimum peak of a sinusoidal wave is reached or when a notified number of cycles has been performed (during tACS). 

PROPRIETARY COMPUTER APPLICATION

nurostym Proprietary SoftwareAll aspects of stimulation can be configured and controlled from the proprietary Windows computer application. Custom stimulation paradigms can saved to one of the preset windows available on the device or delivered via the stimulator as normal. The nurostym app serves as the portal to download stimulation logs and perform software/firmware updates when available.

EXTENDED FUNCTIONALITY

With 7 BNC connections for triggering and arbitrary waveform control, a 15pin D-Type connector and three touchproof connections, the added functionality generated by the new INTERFACE module makes the nurostym truly unrivalled in flexible stimulation options. Multi channel stimulation montages can also be accomplished via the SPLITTER module, allowing the user to enable up to four channels of stimulation with a single active channel. Available as standard with the nurostym.

BUILT-IN PRESETS

Save or load up to eight presets onto the device for quick set up times. These presets can either be protocols which are most used, or in a study which is double blind controlled. Parameters can be hidden via the ‘Study Mode’ option, so a user is not aware of either the type of stimulation being delivered, or whether or not stimulation is active or sham.

MRI-COMPATIBLE SOLUTIONS

MRI-compatible solutions are available as an additional option for the nurostym tES system. The options available are suitable for all types of scanners, including 1.5T, 3T and 7T MRI. Speak to one of our product specialists about adding MRI-compatibility to your nurostym tES.

COMPLEX TRIGGERING OPTIONS AVAILABLE

Configured in the nurostym computer application, the stimulator has five different trigger channels. Two Trigger-In channels and three Trigger-Out options offer a multitude of simple or sophisticated options. Start, stop, number of cyles, peak/trough and polarity change triggers can all be specified.

Number of Channels

1 pair (1 anode, 1 cathode)

Number of Channels, with SPLITTER

4x1 (1 active, 4 return)

Power Supply

Built-in, rechargeable battery

Operating Time

Up to 10 hours

Stimulation Modes

tDCS, tACS, tRNS, Pulsed tDCS, AM-tACS, Analogue Input

Interface

Touch screen display and USB

Sham Modes

None, Single-blind or Double-blind

Maximum Voltage

35V

Digital Triggers

2 digital inputs

3 digital outputs

 

 

tDCS Parameters

 

Stimulation Current

max ±5 mA (increment 1µA)

Stimulation Duration

1-1800s (increment 1s)

Fade In/Out

0-60s (increment 1s)

 

 

tACS / AM-tACS Parameters

 

Stimulation Current (peak-to-peak value)

max 5 mA (increment 1µA)

Offset   

max ±3 mA (increment 1µA)

Stimulation Duration

1-1800s (increment 1s)

Fade In/Out

0-60s (increment 1s)

Frequency (Carrier)

0.01-600Hz (increment 0.01Hz)

Frequency (Modulation)

0-300Hz (increment 0.01Hz)

 

 

Pulsed tDCS Parameters

 

Stimulation Current

max ±5 mA (increment 1µA)

Stimulation Duration

1-1800s (increment 1s)

Fade In/Out

0-60s (increment 1s)

Frequency

0.01 - 600Hz (increment 0.01Hz)

Signal Duty Cycle

1-99% (increment 1%, for freq. <50Hz) 10-90% (increment 1%, for freq. ≥50Hz)

 

 

tRNS Parameters

 

Sample Value Range

±(200 - 5000)µA (increment 1µA)

Stimulation Duration

1-1800s (increment 1s)

Fade In/Out

0-60s (increment 1s)

Noise Distribution

Rectangular, gaussian

Predefined Filters

LP: 100Hz, 250Hz, 640Hz, OFF

HP: 50Hz, 100Hz, 250Hz, OFF

 

 

Analogue Input Parameters

 

Transfer Ratio

2mA per V

Current Range

±5 mA

Analogue Bandwidth

1kHz (-3dB)

 

Compatible Products

This product can be used in combination with some of our other systems. Find out more by selecting one from the list below.

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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