tES-MRI Package

Our tES-MRI upgraded package integrates Transcranial Electrical Stimulation (tES) with Magnetic Resonance Imaging (MRI). The integration of both techniques allows users to deliver safe and concurrent tES studies inside an MRI environment, ensuring simultanious stimulation and high quality brain imaging.

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tES-MRI Package

tES-MRI Package

tES-mri upgrade

The tES-MRI Package is fully compatible with the tES nurostym device and is specifically designed for safe and reliable use in MRI environments. This upgraded package provides all the specialised accessories needed for seamless, full compatibility between a tES nurostym device and MRI systems to support a range of paradigms including tDCS, tACS, tRNS, and multi-channel stimulation. 

nurostym device

The nurostym is a powerful, complete Transcranial Electrical Stimulation (tES) device capable of standard tES modalities: tDCS, tACS, tRNS, pulsed tDCS, amplitiude-modalulated tACS, and analogue input modes. The device offers complete control of stimulation parameters; fully programmable protocols; sham and double-blind controls; advanced safety functions; and user-friendly controls to enable even the most complex of studies using tES

The Nurostym tES-MRI device upgrade:  

 

  • The nurostym supports MRI systems from 1.5T to 7T, offering flexible compatibility for diverse research and clinical environments.
  • The nurostym’s specialised MRI accessories ensure that stimulator hardware and lead routing meet MRI safety standards, keeping patient safety at the forefront of every study. Components are engineered to prevent tissue or device overheating, even during prolonged or high-field MRI sessions, providing researchers with confidence for safe operation. Carefully routed leads, incorporating filtering and RF attenuation, protect MRI data from noise and interference, minimizing artifacts and preserving high-quality, reliable signals during scanning. Together, these features enable safe, consistent, and reproducible simultaneous tES-MRI experiments, supporting robust and trustworthy research outcomes.

  • Trigger-in/out hardware (eg, optical or filtered BNC) to safely integrate stimulation timing with MRI sequence triggers.  
  • The nurostym supports double-blind sham control, analogue signal control, real-time signal output which are all compatible with MRI paradigms. 
  • The nurostym SPLITTER accessory is fully MRI-compatible, with a dedicated cable and setup provided for seamless integration. This accessory allows up to four return channels from a single active channel, offering greater flexibility and control. The nurostym includes a dedicated switch for each channel, enabling users to accurately measure impedance individually and tailor stimulation with precision.

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Seamless Sham Protocols in MRI Studies

Double-blind sham stimulation control is available with the tES-MRI upgrade with a nurostym device. This option allows the researcher to select a pre-defined stimulation protocol. The current delivered will either follow the active stimulation waveform shape, or a pseudo stimulation output. In both cases, the stimulator display will show the same information during real and sham stimulation. 

 

Reliable Triggering for tES in MRI

The triggering capabilities of the tES devices stays the same when applying tES within MRI environments. Brainbox provides a wave guide and custom long cable to connect through the filter panel. The triggering system stays the same as when in regular tES experiments, connected to the computer using a USB input.  

Parameter 

Specification 

MRI Field Strength Compatibility

Configurable for use in 1.5T, 3T, and 7T MRI systems (with dedicated MRI-compatible accessories)

MRI-Rated Stimulation Leads

High-resistance, RF-attenuated cables designed to minimise induced currents and reduce RF heating

Artifact Minimisation

Filtered connections and optimised cable routing to preserve MRI image quality and reduce noise-related artefacts

Trigger Integration

MRI-safe Trigger-In / Trigger-Out via optical or filtered BNC connections for synchronisation with MRI sequences

Maximum Output Current

±5 mA

Maximum Compliance Voltage

±35 V

Stimulation Modes

tDCS, tACS, tRNS, pulsed tDCS

Safety Monitoring

Continuous impedance monitoring with programmable automatic safety cut-off

MRI-Compatible SPLITTER

Supports up to four return channels from a single active channel with independent impedance measurement

 

 

 

Compatible Products

This product can be used in combination with some of our other systems. Find out more by selecting one from the list below.

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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