TMS-EMG Package

Our TMS-EMG complete research package is designed to integrate transcranial magnetic stimulation (TMS) with high-fidelity electromyography (EMG) recordings. By combining advanced stimulation technology with precision signal acquisition, this package enables researchers to explore motor pathways, cortical excitability, and neuromuscular function with unparalleled accuracy.

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TMS-EMG Package

TMS-EMG Package

Includes: DuoMag MP-Dual, DIGITIMER EMG Amplifiers, Brainsight Neuronavigation

 

The TMS-EMG package combines advanced brain stimulation, electrophysiological recording, and navigation systems into one high-performance platform. Designed for precision neuromuscular research, this package enables researchers to investigate motor pathway dynamics, cortical excitability, and neuromuscular responses with synchronised stimulation and high-fidelity EMG signal acquisition.

  • TMS System: The DuoMAG MP-Dual provides fully programmable single and paired-pulse stimulation through a single coil. This allows independent control over pulse intensity and timing—ideal for probing inter-cortical and intra-cortical interactions.

  • EMG System: The integrated EMG solution combines research-grade amplifiers with powerful data acquisition hardware. Adjustable gain, bandwidth, and filtering options ensure accurate capture of TMS-evoked responses, including motor evoked potentials (MEPs).

  • Neuronavigation System: Brainsight TMS Navigation ensures precise coil positioning by aligning stimulation targets with individual MRI scans. This guarantees consistency and reproducibility across subjects and sessions.

Seamless Integration & High-Performance Technology 

This complete solution is optimised for neuromuscular studies, enabling researchers to synchronise TMS delivery with EMG signal acquisition. Whether mapping motor pathways or investigating cortical excitability, the system delivers clean, time-locked physiological data and reproducible targeting.

  • Accurate synchronisation between stimulation and EMG capture.

  • Real-time targeting with MRI-guided coil placement.

  • User-friendly interface for smooth setup, recording, and analysis.

Flexible TMS for Advanced Neurostimulation

With programmable stimulation protocols and dual-pulse capabilities, the DuoMAG MP-Dual offers the flexibility needed for advanced TMS paradigms. Researchers can tailor stimulation protocols to target motor cortex regions with precision.

  • Single and paired-pulse stimulation modes.

  • Independent pulse intensity and interval control.

  • Boosted stimulation output for high-demand studies.

  • CE-certified for safe, research-grade operation.

 

High-Fidelity EMG Recording

The EMG system captures neuromuscular responses with precision. Paired with robust amplifiers and a high-speed data acquisition unit, the system offers clean, synchronised signal recording—optimised for motor evoked potential (MEP) detection and analysis.

Highlights include:

  • Low-noise, high-resolution signal amplification.

  • Adjustable gain and filter settings.

  • Real-time TMS pulse triggering and timestamping.

  • Flexible channel configuration for multi-muscle recordings.

Precision Neuronavigation with Brainsight

Brainsight delivers MRI-guided TMS navigation for reliable, repeatable stimulation. Real-time 3D tracking and anatomical alignment help researchers maintain consistency and target specificity during motor mapping studies.

  • Real-time feedback on coil positioning.

  • Integration with TMS triggers and EMG monitoring.

  • Visualisation of stimulation sites in anatomical context.

  • Support for individualised and group-based studies.

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Synchronous TMS-EMG Data Capture

Accurate temporal alignment of stimulation and muscle activity recording to support reliable MEP measurement and cortical excitability studies.

High-Resolution EMG Recording

Low-noise amplifiers with adjustable gain and bandwidth ensure clean recordings of motor evoked potentials across a range of experimental conditions.

Flexible Stimulation Protocols

Support for single and paired-pulse paradigms enables comprehensive exploration of motor pathways and inter-cortical interactions.

End-to-End Integration

All components work together seamlessly, enabling researchers to focus on experimental design without complex configuration.

Category Specification
TMS Stimulation  
Pulse Type Monophasic paired-pulse via single coil
Inter-Stimulus Interval Fully programmable (1 ms – 10,000 ms)
Output Control Independent per pulse; programmable intensity
Boosted Output Mode Equivalent to 134% of single stimulator output
Cooling Air-cooled with coil temperature monitoring
Certification CE-certified for research use
   
EMG Amplifier  
Channel Count 2–8 channels (expandable depending on model)
Gain Adjustable (up to 10,000x depending on amplifier model)
Bandwidth DC to 10 kHz (user configurable)
Input Type Differential, high impedance
Input Noise < 1 μV RMS (typical)
Filtering Adjustable analog and digital filters
Trigger Input TTL trigger from TMS system for pulse marking
Compatibility Optimised for detecting MEPs
   
Data Acquisition Unit  
Sampling Rate Up to 200 kHz per channel
Resolution 16–24-bit A/D conversion
Synchronisation Hardware-timed trigger alignment with TMS pulses
Data Export Raw data output in CSV, MATLAB, or binary formats
   
Neuronavigation  
Navigation Method Optical tracking with MRI co-registration
Spatial Accuracy ≤ 5 mm (typical)
Coil Feedback Real-time position and angle relative to target
Imaging Compatibility DICOM, Analyze, NIfTI formats
Integration Synchronises with TMS and EMG event triggers
   
General System  
Synchronisation Full integration across TMS, EMG, and Navigation
Software Suite Unified GUI with visualisation, recording, and stimulation control
Applications Motor mapping, MEP detection, cortical excitability, neuromodulation
  1. Unlocking adults’ implicit statistical learning by cognitive depletion. Eleonore H. M. Smalle, Tatsuya Daikoku, Arnaud Szmalec, Wouter Duyck, and Riikka Möttönen. PNAS. January 2022
  2. The interactions between Primary Somatosensory and Motor Cortex during human grasping behaviours. Madison Davis, Yiyu Wang, Shangcheng Bao, John J. Buchanan, David. L Wright, Yuming Lei.. Neuroscience. November 2021
  3. Is the vertex a good control stimulation site? Theta burst stimulation in healthy controls. Dominik Pizem, Lubomira Novakova, Martin Gajdos & Irena Rektorova. Journal of Neural Transmission. 2022
  4. Neuronavigation maximizes accuracy and precision in TMS positioning: Evidence from 11,230 distance, angle, and electric field modeling measurements. Kevin A. Caulfield, Holly H. Fleischmann, Claire E. Cox, Julia P. Wolf, Mark S. George, Lisa M. McTeague. Brain Stimulation. August 2022
  5. Using transcranial magnetic stimulation to map the cortical representation of lower-limb muscles. Davies, J. L.. Clinical Neurophysiology Practice. 2020
  6. Training intensity-dependent increases in corticospinal but not intracortical excitability after acute strength training. Colomer-Poveda, D., Hortobágyi, T., Keller, M., Romero-Arenas, S., & Márquez, G.. Scandinavian Journal of Medicine and Science in Sports. 2020
  7. Novel tools for rapid online data acquisition of the TMS stimulus-response curve. Mark van de Ruit, Tom Pearson and Michael J. Grey. Brain Stimulation, Volume 12, Issue 1, P192-P194. January 2019
  8. A Custom Solution for Acoustic Startle Response Setup with Spike2-Based Data Acquisition Interface. Arsenly Pelevin, Natalia Kurzina, Vladislav Zavialov and Anna Volnova. Biomedical Sciences and Physiology: Methods and Protocols. June 2023

Compatible Products

This product can be used in combination with some of our other systems. Find out more by selecting one from the list below.

Associated Techniques

To find out more about the techniques that are applicable to this product, follow the links below.

Added Value

In addition to supplying and supporting a wide range of neuroscience products, Brainbox offers additional value in a number of areas that can benefit our customers, including:

Training
Installation, Product Training, Technique Training, Bespoke Training

Lab Support
System Upgrades, Testing, Calibration, System Integration, Bespoke Solutions

Research Support
Study Design, Piloting, Technical Information, References

Collaboration
Grant Applications, Industrial Projects, Workshops

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