PROTXX Postural Sway Analysis

What is PROTXX?

The PROTXX system is comprised of three pieces of state-of-the-art neuroscience technology:

• The PROTXX physiological vibration acceleration (phybrata) sensor, which detects microscopic involuntary motions of the body, both normal and pathological
• The PROTXX machine learning engine, which leverages unique features in phybrata signals to identify, quantify, and monitor the treatment of complex neurophysiological impairments throughout the body.
• The PROTXX Clinic platform-as-a-Service (PaaS) solution, which integrates the phybrata sensor, mobile app, and cloud-based data analytics to enable easy-to-use testing in any doctor’s office, research lab, or via remote patient care.

What can PROTXX be used for?

PROTXX’s one-minute, non-invasive Phybrata test is able to identify, quantify, and monitor impairments across multiple physiological systems based on their unique contributions to biomechanical stabilisation of the head and eyes as the reference platform that the body relies on for balance and movement.

The data from the Phybrata test is analysed by PROTXX’s advanced machine learning engine, which is able to derive digital biomarkers that classify various impairments to different physiological systems based on their unique biomechanical vibrational signatures.

The PROTXX system’s combined technologies allow the user to simplify the diagnosis and treatment of neurophysiological impairments. The PROTXX Clinic PaaS solution leverages a growing library of phybrata digital biomarkers to help quantify physiological performance and changes in response to participation in sports, lifestyle changes, injuries, disease, age-related disorders, prescription medications, rehabilitation therapies, surgical procedures, and participation in clinical trials.

Wellness Applications

PROTXX can be used to monitor and limit the effects of head impact exposure in athletes, as well as stratify performance, monitoring recovery from fatigue and injury.

In elderly populations, PROTXX can be used to stratify balance performance, fall risks, and response to balance therapy, as well as provide ageing-in-place support.

Clinical Applications

In a clinical setting, PROTXX is able to support faster, earlier, and more quantitive diagnoses; provide efficient monitoring of physical therapy and rehabilitation, and support administration and clinical trials of disease-modifying therapies by assessing dose and patient response over extended treatment periods.

Applications in Concussion

Concussions lead to a wide range of impact-induced damage locations (brain, vestibular system, visual system, cervical spine), volumes, topologies, and affected CNS, PNS, sensory, vascular, and musculoskeletal structures and functions. PROTXX’s rapid insights into concussions can be invaluable for those working in sports science or with athletes where concussions are a prominent problem.

The phybrata sensor provides concussion researchers, clinicians, and rehabilitation providers with a powerful new tool that can help to:

• identify and quantify impact-induced physiological impairments
• prepare personalized plans to manage, treat, and rehabilitate concussion patients
• accelerate return to functional independence
• reduce the incidence, severity, and duration of longer-term physical disabilities and cognitive impairments.

Applications in Stroke

Stroke leads to a wide range of occlusion/haemorrhage-induced lesion locations (brain, cerebral arteries), volumes, topologies, and affected CNS, PNS, sensory, vascular, and musculoskeletal structures and functions.

• The phybrata sensor provides stroke researchers, clinicians, and rehabilitation providers with a powerful new tool that can help to:
• identify and quantify occlusion/haemorrhage-induced physiological impairments
• prepare personalized plans to manage, treat, and rehabilitate stroke patients
• accelerate return to functional independence
• reduce the incidence, severity, and duration of longer-term physical disabilities and cognitive impairments.

Applications in Multiple Sclerosis

Multiple sclerosis (MS) is an auto-immune disease that causes the demyelination of neurons in the brain and nerves in the spinal cord. MS currently has no cure and leads to debilitating impairments to multiple physiological systems throughout the body. Patients have highly individual impairment profiles, and their symptoms can fluctuate significantly. Available disease-modifying therapies are expensive, have severe side effects, and patients have widely varying responses.

• The phybrata sensor provides MS researchers, clinicians, and physical therapy providers with a powerful new tool that can help to:
• Quantify each patient’s unique MS impairment profile.
• Continuously monitor each patient’s unique response to pharmaceutical or non-pharmaceutical treatments to enable real-time adjustments.
• Slow the progression of longer-term physical disabilities and cognitive impairments.

Applications in Parkinson’s Disease

Parkinson’s Disease (PD) leads to degenerative loss of dopaminergic neurons in the midbrain (substantia nigra) that impairs the function of many other regions of the brain. PD currently has no cure and leads to debilitating impairments to multiple physiological systems throughout the body. Patients have highly individual impairment profiles, and their symptoms can fluctuate significantly. Available disease-modifying therapies are expensive, have severe side effects, and patients have widely varying responses.

The phybrata sensor provides PD researchers, clinicians, and physical therapy providers with a powerful new tool that can help to:

• Quantify each patient’s unique PD impairment profile.
• Continuously monitor each patient’s unique response to pharmaceutical or non-pharmaceutical treatments to enable real-time adjustments.
• Slow the progression of longer-term physical disabilities and cognitive impairments.